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Neuromodulators are your wishes granted in softening undesirable fine lines and unwanted wrinkles that reveal a much smoother and more youthful complexion you have in you. As time progress, facial lines in our faces gradually make their way and start becoming noticeable on our skin. Caused by diminishing collagen or damaging free radicals, neuromodulators help reverse these said effects. In addition, facial expressions that include frowning, squinting, or raising eyebrows create deep wrinkles.

Today, we’ll dive into the skin-deep truth about neuromodulators and how they can help alleviate your skin concerns and regain your youthful glow. Let’s go.  

 All About Neuromodulators

Neuromodulators are injections made of botulinum toxins; wrinkle-relaxing agents effectively soften hard lines in the face. Commercially, these neuromodulators are popularly known as Botox Cosmetic, Dysport, Xeomin, or Jeuveau, to name a few. These are famous treatments used against wrinkles, frown lines, and crow’s feet.

Neuromodulators are agents in rejuvenating the face, relaxing severe wrinkles towards a much softer and more healthy-looking glow. They interrupt the signals transmitted through the nerves and muscles that cause them to contract less, resulting in smoothened-out wrinkles. Small amounts of neuromodulators are directly injected into underlying muscles, causing its relaxation and gradual smoothening out of the appearance of overlying quantities of the skin. Typically, effects brought about by neuromodulators can last for about three (3) months.

Defining Neuromodulation

As defined by the International Neuromodulation Society, Neuromodulation is “the alteration of nerve activity through targeted delivery of a stimulus, such as electrical stimulation or chemical agents, to specific neurological sites in the body.”

Using this definition, we define a neuromodulator as a messenger that gets released from a neuron, eventually affecting the signal transmission between neurons. However, we need to emphasize the difference between a neuromodulator from a neurotransmitter. Although neurotransmitters are also released messengers from neurons; however, they are released to “transmit” or carry messages across specific junctions termed a synapse. These neurotransmitters diffuse across these junctions, affecting at least one (1) or, at times, two (2) of either a postsynaptic neuron, a muscle cell, another effector cell, or any combination of two (2) of these three (3) neuron-related entities.

As our faces get distorted when we smile and make facial gestures, these said facial activities create facial lines and wrinkles that, over time, get more pronounced and noticeable, especially as we age and get older. Over time, surface-level lines started to deepen and become more prominent gradually. Like the famous ones such as Botox, Dysport, and Xeomin, Neuromodulators help reduce these muscle movements, relaxing the fine lines and wrinkles on our faces. Neuromodulators also block acetylcholine release that causes the signal disruption starting from the nerve cells down to the muscles.


Neuromodulators have a broad and general scope and effect on the body’s parts and possible target areas. Typically, some of the most common benefits you can get from neuromodulators are as follows:

  • Fine lines are gradually removed.
  • Wrinkles are significantly reduced.
  • It takes care of frown and forehead lines.
  • Smoothens the forehead and the brows and the presence of Crow’s feet.
  • It softens bunny lines in the nose area.
  • Fine lines around the eyes and the mouth are also reduced.
  • Rejuvenates the neck area.
  • It reduces cases and causes excessive sweating.
  • It is a non-surgical procedure, proven safe, and effective.
  • This treatment is virtually painless.
  • No recovery time is needed, so get back to your daily activities in no time.

Frequently Asked Questions

“Neuromodulators can treat which areas of the body?”

Neuromodulators are a standard treatment for targeted areas of the face, neck, and chin. This procedure can also be used in treating cases and causes of excessive sweating, usually those experienced in the hands and underarms.

“What can you expect from neuromodulators?”

Typical neuromodulation goes like this: Your doctor or healthcare provider will meet with you first, performing a complete examination so that they can determine what injection sites will be most effective. Then, before the actual injection procedure, the proctor cleans the treatment area. Upon your desire and request, the proctors can apply anesthetics or topical creams before proceeding to the neuromodulation treatment. During your neuromodulation, neuromodulator injections are given to the targeted area or areas of concern using a fine needle injected into specific muscles.  

The actual neuromodulation process is relatively fast and easy and can last around 15-30 minutes in general.

“How long do neuromodulation results last?”

Noticeable results should manifest within the next three (3) to seven (7) days after your neuromodulation treatment. Most people claim to have experienced only the mildest of side effects from these injections, typically ranging from bruises, swelling, and discoloration. On average, neuromodulation results can last between the next three (3) to six (6) months.

“When are neuromodulators appropriate?”

Neuromodulators are appropriately used for the following issues and conditions:

  • Fine lines
  • Wrinkles
  • Frown lines
  • Forehead furrows
  • Crow’s feet
  • Aging skin
  • Sagging skin
  • Excessive sweating

“What should be done first before considering neuromodulators?”

Before any cosmetic procedure, a thorough review of your medical history should be attained and reviewed by your doctor or healthcare provider first. During accomplishing and obtaining this said information, you and your doctor should discuss every expectation, potential risk, and possible outcomes the neuromodulation procedure might give. You should disclose to your doctor if you’re using, have recently taken, or have had:

  • Allergy or cold medicine
  • Antibiotics by injection
  • Blood-thinning drugs
  • Muscle relaxants
  • Over-the-counter medication and supplements
  • Previous neuromodulator therapy
  • Sleep medicine

“What can I expect after having had a neuromodulator treatment?”

  • No recovery time is needed after your neuromodulator injections.
  • Ensure to take care and not rub your treated areas, which could cause its migration to other areas of the body.

For excessive sweating:

  • There will be a gradual yet noticeable decrease in sweating within the next two (2) weeks.
  • This reduction will last for six (6) months, so you will need to be treated at least twice per year.

“What are some potential complications from having neuromodulators?”

  • Drooping eyelid
  • Headache
  • Mild bruising
  • Soreness
  • Temporary weakness of surrounding muscles

“Are neuromodulators painful?”

Pain from having neuromodulators is usually minimal to nothing at all. During your treatment, if you request for it, a topical anesthetic, a numbing cream, or an ice pack can be applied and used to your treatment area before your neuromodulation treatment.

“Who cannot be a candidate for neuromodulators?”

Neuromodulation is not appropriate for those who are not in the excellent current, overall physical, mental, and emotional health condition since it may affect the procedure moving forward.

Final Thoughts on Neuromodulators

Neuromodulators can be the thing you’ve been waiting for against all your skin concerns. Make sure to check every information about neuromodulators and what they can give you. Neuromodulators are the revolution towards rejuvenation and overall beautification.

Do you want to know more about neuromodulators? Don’t worry; our amazing friends at Aesthetically Savy Medical Spa will help you out! Visit them now!

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